Mahadeo A. Sukhai

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Alicia M. Cole, Zezhou Wang, Étienne Coyaud et al. · Cancer Cell · 2015 · 349 citations · Full text

Medicine, Oncology, Pharmacology +9

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung et al. · Blood · 2015 · 342 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +17

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial

Tracy Stockley, Amit M. Oza, Hal K. Berman et al. · Genome Medicine · 2016 · 285 citations · Full text

Medicine, Molecular Medicine, Oncology +17

The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

Paul A. Spagnuolo, Jiayi Hu, Rose Hurren et al. · Blood · 2010 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

Sumaiya Sharmeen, Marko Škrtić, Mahadeo A. Sukhai et al. · Blood · 2010 · 145 citations · Full text

Medicine, Cell Biology, Pharmacology +16