Jason Moffat

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht et al. · Genome biology · 2006 · 5.4K citations · Full text

A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen

Jason Moffat, Dorre A. Grueneberg, Xiaoping Yang et al. · Cell · 2006 · 1.8K citations · Full text

Viral Replication, Molecular Virology, Immunology +9

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

Traver Hart, Megha Chandrashekhar, Michael Aregger et al. · Cell · 2015 · 1.7K citations · Full text

Genotype-specific Cancer Liabilities, Engineering, Genetics +9

Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

David A. Guertin, Deanna M. Stevens, Carson C. Thoreen et al. · Developmental Cell · 2006 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate

Gregory Huyer, Susana Liu, John A. Kelly et al. · Journal of Biological Chemistry · 1997 · 825 citations · Full text