Tumor microenvironments self-activated nanoscale metal-organic frameworks for ferroptosis based cancer chemodynamic/photothermal/chemo therapy

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 17K citations · Full text

Iron Deficiency, Nonapoptotic Cell Death, Metalloprotein +9

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.1K citations · Full text

Tumor Biology, Medicine, Apoptosis +5

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 3.8K citations · Full text

Proteinlipid Interaction, Biochemistry, Natural Sciences +4

Ferroptosis as a p53-mediated activity during tumour suppression

Le Jiang, Ning Kon, Tongyuan Li et al. · Nature · 2015 · 3.2K citations · Full text

Cancer Research, Medicine, Pathology +9

Production of large amounts of hydrogen peroxide by human tumor cells.

Ted P. Szatrowski, Carl Nathan · PubMed · 1991 · 2.5K citations

Redox Signaling, Tumor Biology, Human Tumor Cells +15