Concepedia

DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells

Can Li, Weiwei Liu, Fang Wang, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima

Molecular Immunology · 2021 · 101 citations · 41 references

DOI

Concepts

References

41

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Liufu Deng, Hua Liang, Meng Xu et al. · Immunity · 2014 · 2.1K citations · Full text

, , +17

cGAS surveillance of micronuclei links genome instability to innate immunity

Karen J. Mackenzie, Paula Carroll, Carol-Anne Martin et al. · Nature · 2017 · 1.7K citations · Full text

, , +13

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

Daxing Gao, Jiaxi Wu, You-Tong Wu et al. · Science · 2013 · 988 citations

, , +15

Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1

Takayuki Abe, Glen N. Barber · Journal of Virology · 2014 · 746 citations · Full text

, , +17

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

Gillian Dunphy, Sinéad Flannery, Jessica F. Almine et al. · Molecular Cell · 2018 · 655 citations · Full text

, , +17