Concepedia

Dextran-modified Quercetin-Cu(II)/hyaluronic acid nanomedicine with natural poly(ADP-ribose) polymerase inhibitor and dual targeting for programmed synthetic lethal therapy in triple-negative breast cancer

Hung‐Wei Cheng, Chih‐Sheng Chiang, Hsin-Yao Ho, Syun-Hong Chou, Yen‐Ho Lai, Woei‐Cherng Shyu, San-Yuan Chen

Journal of Controlled Release · 2020 · 32 citations · 27 references

DOI

Concepts

References

27

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

, , +16

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

, , +12

Pathology of Breast and Ovarian Cancers among <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers: Results from the Consortium of Investigators of Modifiers of <i>BRCA1</i> / <i>2</i> (CIMBA)

Nasim Mavaddat, Daniel Barrowdale, Irene L. Andrulis et al. · Cancer Epidemiology Biomarkers & Prevention · 2012 · 668 citations · Full text

, , +15

Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy

Joo Eun Chung, Susi Tan, Shu Jun Gao et al. · Nature Nanotechnology · 2014 · 417 citations · Full text

, , +17

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells11Edited by J. Karn

Catherine Arnaudeau, Cecilia Lundin, Thomas Helleday · Journal of Molecular Biology · 2001 · 384 citations

, , +15