Concepedia

Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway

Meng‐Fei An, Mingyue Wang, Chang Shen, Ze‐Rui Sun, Yun‐Li Zhao, Xuanjun Wang, Jun Sheng

Journal of Natural Medicines · 2020 · 31 citations · 47 references

DOI

Concepts

References

47

Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007-2008

Yanyan Zhu, Bhavik J. Pandya, Hyon K. Choi · Arthritis & Rheumatism · 2011 · 1.8K citations · Full text

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Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: Assessment of Medication Risks with Emphasis on Recently Marketed Drugs. The EuroSCAR-Study

Maja Mockenhaupt, Cécile Viboud, Ariane Dunant et al. · Journal of Investigative Dermatology · 2007 · 998 citations · Full text

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Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion

Cristofer Enroth, B.T. Eger, Ken Okamoto et al. · Proceedings of the National Academy of Sciences · 2000 · 718 citations · Full text

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Soluble Uric Acid Activates the NLRP3 Inflammasome

Tárcio Teodoro Braga, Maria Fernanda Forni, Matheus Corrêa-Costa et al. · Scientific Reports · 2017 · 423 citations · Full text

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Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Tania O. Crișan, Maartje C. P. Cleophas, Marije Oosting et al. · Annals of the Rheumatic Diseases · 2015 · 277 citations

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