Maartje C. P. Cleophas

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial

Viola Klück, Tim Jansen, M. Janssen et al. · The Lancet Rheumatology · 2020 · 290 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Tania O. Crișan, Maartje C. P. Cleophas, Marije Oosting et al. · Annals of the Rheumatic Diseases · 2015 · 277 citations

Veterinary Medicine, Immunology, Pathobiology +15

Effect of Vegan Fecal Microbiota Transplantation on Carnitine‐ and Choline‐Derived Trimethylamine‐N‐Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome

Loek P. Smits, Ruud S. Kootte, Evgeni Levin et al. · Journal of the American Heart Association · 2018 · 242 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +13

Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway

Tania O. Crișan, Maartje C. P. Cleophas, Boris Novakovic et al. · Proceedings of the National Academy of Sciences · 2017 · 160 citations

Life Sciences, Cell Biology, Immunology +17

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Maartje C. P. Cleophas, Tania O. Crișan, Heidi Lemmers et al. · Annals of the Rheumatic Diseases · 2015 · 136 citations

Life Sciences, Immunology, Pharmacology +17