Regulation of peroxisome proliferator-activated receptor-gamma activity affects the hepatic stellate cell activation and the progression of NASH via TGF-β1/Smad signaling pathway

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher et al. · Nature Medicine · 2007 · 1.9K citations

Inflammation, Fibrosis, Hepatology +11

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Ingmar Mederacke, Christine Hsu, Juliane S. Troeger et al. · Nature Communications · 2013 · 1.4K citations · Full text

Fibrosis, Developmental Biology, Hepatology +15

Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis

Xuelian Xiong, Henry Kuang, Sahar Ansari et al. · Molecular Cell · 2019 · 740 citations · Full text

Cell Lineage, Systems Biology, Single Cell Sequencing +12

High-yield and high-purity isolation of hepatic stellate cells from normal and fibrotic mouse livers

Ingmar Mederacke, Dianne H. Dapito, Silvia Affò et al. · Nature Protocols · 2015 · 537 citations

Fibrosis, Hepatology, Hepatic Stellate Cells +15

Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells

Fabio Marra, Eva Efsen, Roberto Giulio Romanelli et al. · Gastroenterology · 2000 · 399 citations

Inflammation, Molecular Pharmacology, Hepatology +14