Concepedia

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher, Johannes Kluwe, Yosuke Osawa, David A. Brenner, Robert F. Schwabe

Nature Medicine · 2007 · 1.9K citations · 42 references

DOI

Concepts

References

42

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Seth Rakoff-Nahoum, Justin C. Paglino, Fatima Eslami-Varzaneh et al. · Cell · 2004 · 4.2K citations · Full text

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NF-κB functions as a tumour promoter in inflammation-associated cancer

Eli Pikarsky, Rinnat M. Porat, Ilan Stein et al. · Nature · 2004 · 2.4K citations

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Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

, , +14

Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

, , +17

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

Jeremy S. Duffield, Stuart J. Forbes, Christothea M. Constandinou et al. · Journal of Clinical Investigation · 2005 · 1.4K citations · Full text

, , +17