Johannes Kluwe

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki, Samuele De Minicis, Christoph H. Österreicher et al. · Nature Medicine · 2007 · 1.9K citations

Life Sciences, Immunology, Molecular Biology +14

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

Zobair M. Younossi, Vlad Ratziu, Rohit Loomba et al. · The Lancet · 2019 · 1.2K citations · Full text

Medicine, Internal Medicine, Pharmacology +8

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

Jean‐Philippe Pradère, Johannes Kluwe, Samuele De Minicis et al. · Hepatology · 2013 · 597 citations · Full text

Life Sciences, Immunology, Pathology +17

CCR1 and CCR5 promote hepatic fibrosis in mice

Ekihiro Seki, Samuele De Minicis, Geum‐Youn Gwak et al. · Journal of Clinical Investigation · 2009 · 435 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Gene Expression Profiles During Hepatic Stellate Cell Activation in Culture and In Vivo

Samuele De Minicis, Ekihiro Seki, Hiroshi Uchinami et al. · Gastroenterology · 2007 · 424 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14