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Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells

Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, Rachel Culp‐Hill, Angelo D’Alessandro, Amanda Winters, Anna Krug, Diana Abbott, Madeline Goosman, Shanshan Pei,

Nature Cancer · 2020 · 305 citations · 34 references

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34

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

Courtney D. DiNardo, Brian A. Jonas, Vinod Pullarkat et al. · New England Journal of Medicine · 2020 · 2.8K citations · Full text

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Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia

Courtney D. DiNardo, Keith W. Pratz, Vinod Pullarkat et al. · Blood · 2018 · 1.9K citations · Full text

, , +11

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

Eleni D. Lagadinou, Alexander Sach, Kevin P. Callahan et al. · Cell stem cell · 2013 · 1.4K citations · Full text

, , +12

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1.1K citations

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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Thomas Farge, Estelle Saland, Fabienne de Toni et al. · Cancer Discovery · 2017 · 916 citations · Full text

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