Emerging Microbes & Infections · 2020 · 100 citations · 47 references
Life SciencesCell BiologyImmunologyCellular ImmunologyMolecular ImmunologyMolecular VirologyAntiviral ImmunityCellular Immunity In InfectionImmunodeficiency DisordersT Cell ActivationT Cell BiologyT Cell ExhaustionCd8 Positive T Cell ResponsesCd8 Positive T CellsExhaustion MarkersHiv-associated ImmunosuppressionLymphocyte ExhaustionSingle-cell Rna SequencingT-cell Immune ResponsesTerminally Exhausted T Cells
population to T cell exhaustion and providing an immunotherapy target to treat HIV chronic infection. These data provide a comprehensive analysis of gene signatures associated with immune cell exhaustion during HIV infection, which could be useful in understanding exhaustion mechanisms and developing new cure therapies.
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Single-cell mRNA quantification and differential analysis with Census
Xiaojie Qiu, Andrew J. Hill, Jonathan S. Packer et al. · Nature Methods · 2017 · 2.1K citations