Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Alexandra–Chloé Villani, Rahul Satija, Gary Reynolds, +21

Science

Spatially organized multicellular immune hubs in human colorectal cancer

Karin Pelka, Matan Hofree, Jonathan Chen, +69

Cell

Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

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Immunity

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A large peptidome dataset improves HLA class I epitope prediction across most of the human population

Siranush Sarkizova, Susan Klaeger, Phuong M. Le, +22

Nature Biotechnology

HlaHistocompatibilityImmunogeneticsAutoimmune DiseaseHuman Leukocyte Antigen +12

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Zhuting Hu, Donna Leet, Rosa Lundbye Allesøe, +38

Nature Medicine

VaccinationTumor ImmunologyEpitope SpreadingCancer ImmunosurveillancePersonal Neoantigen Vaccines +9

Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages

Christel Goudot, Alice Coillard, Alexandra–Chloé Villani, +9

Immunity

InflammationAutoimmune DiseaseGranulocyteImmune RegulationImmunology +7

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

Bob Chen, Cherie’ R. Scurrah, Eliot T. McKinley, +49

Cell

Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer

Tamara Ouspenskaia, Travis Law, Karl R. Clauser, +26

Nature Biotechnology

Cancer ImmunosurveillanceImmunologyImmunoeditingAntigen ProcessingAutoimmunity +5

Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq

Bo Li, Joshua Gould, Yiming Yang, +11

Nature Methods

EngineeringCloud-based Data AnalysisTranscriptomics TechnologyTrajectory AnalysisSingle Cell Sequencing +15

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Alexandra–Chloé Villani, Rahul Satija, Gary Reynolds, +21

DSpace@MIT (Massachusetts Institute of Technology)