Concepedia

OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING

Yunyun Guo, Fei Jiang, Lingli Kong, Haifeng Wu, Honghai Zhang, Xiaorong Chen, Jian Zhao, Baoshan Cai, Yanqi Li, Chunhong Ma,

Cellular and Molecular Immunology · 2020 · 101 citations · 28 references

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28

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

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Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Jiaxi Wu, Lijun Sun, Xiang Chen et al. · Science · 2012 · 2.5K citations

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Liufu Deng, Hua Liang, Meng Xu et al. · Immunity · 2014 · 2.1K citations · Full text

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Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

Siqi Liu, Xin Cai, Jiaxi Wu et al. · Science · 2015 · 1.9K citations

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The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

Bo Zhong, Yan Yang, Shu Li et al. · Immunity · 2008 · 1.5K citations · Full text

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