The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

Bo Zhong, Yan Yang, Shu Li, +8

Immunity

Signal TransductionMolecular VirologyImmunologyVirologyVirus-host Interaction +4

RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak

Liangjun Chen, Weiyong Liu, Zhang Qi, +14

Emerging Microbes & Infections

Virus EpidemiologyViral DiagnosticsViral PathogenesisPathologyTotal Rna +19

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

Xindong Liu, Yun Wang, Huiping Lu, +26

Nature

Signal TransductionAutoimmune DiseaseT Cell DysfunctionT-regulatory CellImmunology +6

The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA

Bo Zhong, Lu Zhang, Cao‐Qi Lei, +6

Immunity

Viral ReplicationProtein FunctionImmunologyAntiviral ResponseCell Biology +4

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development

Xindong Liu, Xin Chen, Bo Zhong, +15

Nature

Transcriptional RegulationCell LineageDevelopmental BiologyCell RegulationLymphocyte Development +5

Bcl6 expression specifies the T follicular helper cell program in vivo

Xindong Liu, Xiaowei Yan, Bo Zhong, +10

The Journal of Experimental Medicine

Immunological MemoryBcl6 ExpressionSignal TransductionDevelopmental BiologyT Cell Differentiation +13

iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING

Wei‐Wei Luo, Shu Li, Chen Li, +4

Nature Immunology

Host ResponseViral ReplicationNatural SciencesAdaptor StingPathogenesis +11

Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein

Tao Xu, Xiaohu Wang, Bo Zhong, +3

Journal of Biological Chemistry

ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response

Ying Li, Chao Li, Peng Xue, +7

Proceedings of the National Academy of Sciences

Viral ReplicationViral PathogenesisImmunologyIfn-stimulated Gene 56Cell Signaling +14

RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms

Yue Qin, Maotian Zhou, Ming‐Ming Hu, +5

PLoS Pathogens

Distinct MechanismsViral ReplicationImmunologyViral PathogenesisImmune Regulation +20