Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption

Sophie D. Adams, Judit Csere, Gisela D’Angelo, Edward Carter, Maryse Romao, Teresa Arnandis, Martin Dodel, Hemant M. Kocher, Richard Grose, Graça Raposo,

Current Biology · 2021 · 73 citations · 48 references

DOIFull text

Open access

Concepts

Abstract

EVs secreted by cancer cells with amplified centrosomes influence the bidirectional communication between the tumor cells and the surrounding stroma to promote malignancy.

References

48