Discovery of a coumarin derivative as Nrf2 activator mitigating oxidative stress and fibrosis in mesangial cells under high glucose

Chemistry and biology of reactive oxygen species in signaling or stress responses

Bryan C. Dickinson, Christopher J. Chang · Nature Chemical Biology · 2011 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +14

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

Anju Singh, Sreedhar Venkannagari, Kyu Hee Oh et al. · ACS Chemical Biology · 2016 · 613 citations

Medicine, Oncology, Pharmacology +16

Nrf2 activation through the inhibition of Keap1–Nrf2 protein–protein interaction

Sumi Lee, Longqin Hu · Medicinal Chemistry Research · 2020 · 127 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

BML-111 attenuates high glucose-induced inflammation, oxidative stress and reduces extracellular matrix accumulation via targeting Nrf2 in rat glomerular mesangial cells

Xiaoming Wu, Congqing Pan, Rui Chen et al. · International Immunopharmacology · 2019 · 32 citations

Medicine, Cell Biology, Nephrology +17

Sikokianin A from <i>Wikstroemia indica</i> protects PC12 cells against OGD/R-induced injury via inhibiting oxidative stress and activating Nrf2

Huankai Yao, Wenting Zhang, Huiling Wu et al. · Natural Product Research · 2018 · 25 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17