Concepedia

Mesangial Cell Dysfunction

Mesangial Cell Dysfunction is a pathophysiological construct characterized by abnormal regulatory, contractile, phagocytic, or proliferative activities of mesangial cells within the glomerulus, leading to disrupted glomerular filtration dynamics and extracellular matrix homeostasis.

849

Publications

41.9K

Citations

4.4K

Authors

997

Institutions

Publications per year

2017–2026

185

Parents

Publications

849

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors

Mitsuo Kato, Jane Zhang, Mei Wang et al. · Proceedings of the National Academy of Sciences · 2007 · 699 citations · Full text

, , +17

Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats

Leopoldo Raij, Silvia Azar, William F. Keane · Kidney International · 1984 · 682 citations

, , +16

Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.

Daisuke Koya, M.R. Jirousek, Y W Lin et al. · Journal of Clinical Investigation · 1997 · 537 citations · Full text

, , +16

Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor.

Toshio Doi, Helen Vlassara, Martina Kirstein et al. · Proceedings of the National Academy of Sciences · 1992 · 353 citations

, , +17

Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway

Vicki Thallas‐Bonke, Suzanne R. Thorpe, Melinda T. Coughlan et al. · Diabetes · 2007 · 346 citations · Full text

, , +16

1–5 of 849

Authors

4.4K

  1. JP
    Josef Pfeilschifter

    Goethe University Frankfurt, Germany

    9 publications · 440 citations

    9

    h-index

  2. CW
    Catharine Whiteside

    University of Toronto, Canada

    9 publications · 493 citations

    9

    h-index

  3. PC
    Pravin C. Singhal

    Long Island Jewish Medical Center, United States

    9 publications · 337 citations

    9

    h-index

  4. DK
    Daisuke Koya

    Kanazawa Medical University, Japan

    7 publications · 1K citations

    7

    h-index

  5. LR
    Leopoldo Raij

    University of Miami, United States

    7 publications · 1.2K citations

    7

    h-index

1–5 of 4.4K

Institutions

997

  1. University of Toronto

    Toronto, Canada

    19 h-index

    92 publications

    6K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    53 publications

    9.2K citations

  3. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    12 h-index

    53 publications

    3.2K citations

  4. Friedrich-Alexander-Universität Erlangen-Nürnberg

    Erlangen, Germany

    12 h-index

    39 publications

    1.4K citations

  5. University of Michigan

    Ann Arbor, United States

    12 h-index

    42 publications

    2K citations

  6. Anhui Medical University

    Hefei, China

    12 h-index

    46 publications

    2.7K citations

  7. Sun Yat-sen University

    Guangzhou, China

    12 h-index

    84 publications

    4.4K citations

  8. Kyoto University

    Kyoto, Japan

    11 h-index

    85 publications

    4.8K citations

1–8 of 997

Venues

  1. Kidney International

    131 publications · 8.6K citations

    55

    h-index

  2. Journal of the American Society of Nephrology

    37 publications · 2.3K citations

    29

    h-index

  3. PubMed

    Repository · 61 publications · 2.4K citations

    28

    h-index

  4. American Journal of Physiology-Renal Physiology

    35 publications · 1.9K citations

    24

    h-index

  5. Diabetes

    25 publications · 3K citations

    23

    h-index

1–5