Nature Medicine · 2020 · 140 citations · 55 references
Life SciencesImmunologyOncologyCancer ImmunologyImmunotherapyTumor ImmunologyCancer ImmunotherapyCheckpoint Inhibitor TherapyImmune Checkpoint InhibitorsImmune Checkpoint RegulationImmune CheckpointsTumor ImmunopathologyPeripheral Immune RegulationProgrammed Cell Death Ligand 1 InhibitionProgrammed Cell Death Protein 1 (Pd-1) PathwayProgrammed Cell Death Protein 1 InhibitorsProgrammed Death-1 BlockadeProgrammed Death-ligand 1 InhibitionProgrammed Death-ligand 1 Inhibitors
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PD-1 blockade induces responses by inhibiting adaptive immune resistance
Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley et al. · Nature · 2014 · 6.6K citations · Full text
Life Sciences, Immunology, Pathology +14
PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
Stephen M. Ansell, Alexander M. Lesokhin, Ivan Borrello et al. · New England Journal of Medicine · 2014 · 3.5K citations · Full text
Medicine, Oncology, Pharmacology +17
An immunogenic personal neoantigen vaccine for patients with melanoma
Patrick A. Ott, Zhuting Hu, Derin B. Keskin et al. · Nature · 2017 · 2.9K citations
Medicine, Immunology, Oncology +12
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
Se Jin Im, Masao Hashimoto, Michael Y. Gerner et al. · Nature · 2016 · 2.1K citations · Full text