<scp>CreLite</scp> : An optogenetically controlled Cre/ <scp>loxP</scp> system using red light

Abstract

Our data show that CreLite can be used for gene manipulations in whole embryos or small groups of cells at different developmental stages, and suggests CreLite may also be useful for temporal and spatial control of gene expression in cell culture, ex vivo organ culture, and other animal models.