Concepedia

Cell-type-specific Regulatory Elements

Cell Type-Specific Regulatory Elements is a class of cis-regulatory DNA sequences that selectively modulate gene expression in a defined cell type due to the presence of unique combinations of transcription factor binding sites and epigenetic marks distinguishing them from regulatory elements active in other cell types.

223

Publications

31.2K

Citations

1.8K

Authors

495

Institutions

Publications per year

2017–2026

78

Variants

Cell-type Specific Regulatory Elements

Parents

Publications

223

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

, , +14

A rapid and robust method for single cell chromatin accessibility profiling

Xi Chen, Ricardo J. Miragaia, Kedar Nath Natarajan et al. · Nature Communications · 2018 · 1.3K citations · Full text

, , +17

Activation of Cell-Specific Expression of Rat Growth Hormone and Prolactin Genes by a Common Transcription Factor

Christian Nelson, Vivian R. Albert, Harry P. Elsholtz et al. · Science · 1988 · 527 citations

, , +17

Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

Jean Fan, Neeraj Salathia, Rui Liu et al. · Nature Methods · 2016 · 440 citations · Full text

, , +16

A transcriptional hierarchy involved in mammalian cell-type specification

Calvin J. Kuo, Pamela B. Conley, Lei Chen et al. · Nature · 1992 · 429 citations

, , +14

1–5 of 223

Authors

1.8K

  1. GE
    Gregory E. Crawford

    Duke University, United States

    7 publications · 683 citations

    7

    h-index

  2. NA
    Nadav Ahituv

    University of California, San Francisco, United States

    6 publications · 564 citations

    6

    h-index

  3. KS
    Katherine S. Pollard

    Gladstone Institutes, United States

    5 publications · 501 citations

    5

    h-index

  4. KZ
    Kai Zhang

    University of California San Diego, United States

    5 publications · 557 citations

    5

    h-index

  5. PF
    Pawel F. Przytycki

    Chan Zuckerberg Initiative (United States), United States

    5 publications · 501 citations

    5

    h-index

1–5 of 1.8K

Institutions

495

  1. Harvard University

    Cambridge, United States

    20 h-index

    90 publications

    8.1K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    34 publications

    5K citations

  3. University of Washington

    Seattle, United States

    13 h-index

    47 publications

    3.1K citations

  4. National Institutes of Health

    Bethesda, United States

    13 h-index

    77 publications

    3.9K citations

  5. University of California San Diego

    San Diego, United States

    12 h-index

    93 publications

    97K citations

  6. University of California, San Francisco

    San Francisco, United States

    11 h-index

    53 publications

    4.9K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    10 h-index

    23 publications

    1.9K citations

  8. Broad Institute

    Cambridge, United States

    9 h-index

    36 publications

    2.6K citations

1–8 of 495

Venues

  1. Molecular and Cellular Biology

    MCB · 23 publications · 1.1K citations

    16

    h-index

  2. Journal of Biological Chemistry

    JBC · 16 publications · 1.1K citations

    15

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 18 publications · 330 citations

    13

    h-index

  4. Nature Communications

    11 publications · 2.1K citations

    11

    h-index

  5. Nucleic Acids Research

    10 publications · 697 citations

    10

    h-index

1–5