Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Takeshi Nishikawa, Diane Edelstein, Xue Du et al. · Nature · 2000 · 4.2K citations

Metabolic Syndrome, Biochemistry, Mitochondrial Function +11

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells.

Toyoshi Inoguchi, Pan Li, F. Umeda et al. · Diabetes · 2000 · 1.6K citations · Full text

Lipid Peroxidation, Reactive Oxygen Species, Redox Biology +21

Glucose Challenge Stimulates Reactive Oxygen Species (ROS) Generation by Leucocytes

Priya Mohanty, Wael Hamouda, Rajesh Garg et al. · The Journal of Clinical Endocrinology & Metabolism · 2000 · 601 citations

Heme oxygenase-1 protects against vascular constriction and proliferation

Henricus J. Duckers, Manfred Boehm, Andrea L. True et al. · Nature Medicine · 2001 · 525 citations

Heme Oxygenase-1 Protects, Physiology, Heme Signaling +6

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling

Takayuki Shindo, Ichiro Manabe, Yasushi Fukushima et al. · Nature Medicine · 2002 · 389 citations

Hypertension, Signal Transduction, Molecular Physiology +12