Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

Durba Pal, Suman Dasgupta, Rakesh Kundu et al. · Nature Medicine · 2012 · 893 citations

Endogenous Ligand, Metabolic Syndrome, Fetuin-a Acts +12

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

Kosei Eguchi, Ichiro Manabe, Yumiko Tanaka et al. · Cell Metabolism · 2012 · 508 citations · Full text

Inflammation, Metabolic Syndrome, Insulin Signaling +12

Fatty acid‐induced induction of Toll‐like receptor‐4/nuclear factor‐κB pathway in adipocytes links nutritional signalling with innate immunity

Andreas Schaeffler, Roland Buettner, Cornelius Bollheimer et al. · Immunology · 2008 · 354 citations · Full text

Immunology, Immune Regulation, Innate Immunity +22

Saturated Fatty Acids Do Not Directly Stimulate Toll-Like Receptor Signaling

Clett Erridge, Nilesh J. Samani · Arteriosclerosis Thrombosis and Vascular Biology · 2009 · 256 citations · Full text

NF-κB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance

Suman Dasgupta, Sushmita Bhattacharya, Anindita Biswas et al. · Biochemical Journal · 2010 · 167 citations

Immunology, Fatty Liver Disease, Adipocyte Function +22