Concepedia

Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs

Yiming Li, Rong‐Hua Luo, Liu‐Meng Yang, Siming Huang, Sui-Yuan Li, Dongxuan Ni, Yi-Man Cui, Xing‐Jie Zhang, Xiao‐Li Li, Ruihan Zhang,

Bioorganic Chemistry · 2020 · 12 citations · 34 references

DOI

Concepts

References

34

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.8K citations

, , +17

Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

Diana Finzi, Monika Hermankova, Theodore C. Pierson et al. · Science · 1997 · 3.1K citations

, , +17

[16] SHELXL: High-resolution refinement

George M. Sheldrick, T. Schneider · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 2.5K citations

, , +4

A semiempirical free energy force field with charge‐based desolvation

Ruth Huey, Garrett M. Morris, Arthur J. Olson et al. · Journal of Computational Chemistry · 2007 · 2.2K citations · Full text

, , +17

A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine

Tadashi Miyasaka, Hiromichi Tanaka, Masanori Baba et al. · Journal of Medicinal Chemistry · 1989 · 382 citations · Full text

, , +12