Lysosomal dysfunction in osteoarthritis and aged cartilage triggers apoptosis in chondrocytes through BAX mediated release of Cytochrome c

Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury.

Changmeng Cui, Jianzhong Cui, Feng Jin et al. · PubMed · 2017 · 5.2K citations

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The role of autophagy in neurodegenerative disease

Ralph A. Nixon · Nature Medicine · 2013 · 2K citations

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Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

Alfredo Ramı́rez, André Heimbach, Jan Gründemann et al. · Nature Genetics · 2006 · 1.2K citations

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LAMP proteins are required for fusion of lysosomes with phagosomes

Kassidy K. Huynh, Eeva‐Liisa Eskelinen, Cameron C. Scott et al. · The EMBO Journal · 2007 · 685 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

Patricia Boya, Karine Andréau, Delphine Poncet et al. · The Journal of Experimental Medicine · 2003 · 474 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17