Concepedia

Pan-retroviral Nucleocapsid-Mediated Phase Separation Regulates Genomic RNA Positioning and Trafficking

Anne Monette, Meijuan Niu, Lois Chen, Shringar Rao, Robert J. Gorelick, Andrew J. Mouland

Cell Reports · 2020 · 118 citations · 153 references

DOIFull text

Open access

Concepts

Abstract

-dependent feature of virus replication represents a critical target for pan-antiretroviral therapies.

References

153

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

Clifford P. Brangwynne, Christian R. Eckmann, David S. Courson et al. · Science · 2009 · 3.3K citations

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Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

Amandine Molliex, Jamshid Temirov, Jihun Lee et al. · Cell · 2015 · 2.8K citations

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Phase transitions in the assembly of multivalent signalling proteins

Pilong Li, Sudeep Banjade, Hui-Chun Cheng et al. · Nature · 2012 · 2.7K citations

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A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

Jie Wang, Jeong‐Mo Choi, Alex S. Holehouse et al. · Cell · 2018 · 2.2K citations · Full text

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

Jonathan J. Ward, Jaspreet Singh Sodhi, Liam J. McGuffin et al. · Journal of Molecular Biology · 2004 · 2.1K citations

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