Concepedia

Enhancement of abiraterone acetate oral bioavailability by supersaturated-silica lipid hybrids

Hayley B. Schultz, Anthony Wignall, Nicky Thomas, Clive A. Prestidge

International Journal of Pharmaceutics · 2020 · 30 citations · 41 references

Concepts

PharmacyClinical PharmacokineticsBioavailabilityDrug DeliveryOral Drug DeliveryBioavailability EnhancementLipid-based Drug Delivery SystemsLipid-based Oral FormulationsLipidomicsOral BioavailabilityOral Bioavailability EnhancementAbsolute Oral BioavailabilityLipid Composition DesignLipid Composition OptimizationOral Bioavailability Optimization

References

41

Abiraterone and Increased Survival in Metastatic Prostate Cancer

Johann S. de Bono, Christopher J. Logothetis, Arturo Molina et al. · New England Journal of Medicine · 2011 · 4.4K citations · Full text

Medicine, Oncology, Pharmacology +17

Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial

Karim Fizazi, NamPhuong Tran, Luis Fein et al. · The Lancet Oncology · 2019 · 813 citations · Full text

Medicine, Oncology, Pharmacotherapy +16

Lipid-based vehicles for the oral delivery of poorly water soluble drugs

Andrew Humberstone, William N. Charman · Advanced Drug Delivery Reviews · 1997 · 579 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconazole Therapy

Charles J. Ryan, Matthew R. Smith, Lawrence Fong et al. · Journal of Clinical Oncology · 2010 · 395 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Non-compartmental Analysis

Johan Gabrielsson, Daniel Weiner · Methods in molecular biology · 2012 · 261 citations

Pharmacy, Pharmacokinetics, Pharmacology +14