Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

Medicine, Oncology, Pharmacology +10

Microtubule Assembly in the Absence of Added Nucleotides

Michael L. Shelanski, Felicia Gaskin, Charles R. Cantor · Proceedings of the National Academy of Sciences · 1973 · 2.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity

Peter J. Houghton, Rui Fang, Isariya Techatanawat et al. · Methods · 2007 · 333 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

A Phase II Trial of Fosbretabulin in Advanced Anaplastic Thyroid Carcinoma and Correlation of Baseline Serum-Soluble Intracellular Adhesion Molecule-1 with Outcome

Colin Mooney, Govardhanan Nagaiah, Pingfu Fu et al. · Thyroid · 2009 · 182 citations

Medicine, Oncology, Pharmacology +12

Kinase Domain Mutations in Cancer: Implications for Small Molecule Drug Design Strategies

Jack Bikker, Natasja Brooijmans, Allan Wissner et al. · Journal of Medicinal Chemistry · 2009 · 163 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14