Tailoring guanidyl-rich polymers for efficient cytosolic protein delivery

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

Paul A. Wender, Dennis J. Mitchell, Kanaka Pattabiraman et al. · Proceedings of the National Academy of Sciences · 2000 · 1.6K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

John A. Zuris, David B. Thompson, Yilai Shu et al. · Nature Biotechnology · 2014 · 1.5K citations · Full text

Pharmacy, Biotechnology, Molecular Genetics +12

Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles

Ming Wang, John A. Zuris, Fantao Meng et al. · Proceedings of the National Academy of Sciences · 2016 · 618 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Role of Membrane Potential and Hydrogen Bonding in the Mechanism of Translocation of Guanidinium-Rich Peptides into Cells

Jonathan B. Rothbard, Theodore C. Jessop, Richard S. Lewis et al. · Journal of the American Chemical Society · 2004 · 614 citations

Life Sciences, Biochemistry, Cell Biology +17

Direct Cytosolic Delivery of CRISPR/Cas9-Ribonucleoprotein for Efficient Gene Editing

Rubul Mout, Moumita Ray, Gülen Yesilbag Tonga et al. · ACS Nano · 2017 · 562 citations

Life Sciences, Genetics, Molecular Genetics +17