Protein kinase 2 (CK2) controls CD4+ T cell effector function in the pathogenesis of colitis

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Birgit Oppmann, Robin Lesley, Bianca Blom et al. · Immunity · 2000 · 2.8K citations · Full text

Life Sciences, Immunology, Cell Signaling +9

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Mark H. Kaplan, Ya‐Lin Sun, Timothy Hoey et al. · Nature · 1996 · 1.2K citations

Life Sciences, Immunology, Pathology +16

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-γ, whereas ulcerative colitis LP cells manifest increased secretion of IL-5

Ivan J. Fuss, Markus F. Neurath, Monica Boirivant et al. · The Journal of Immunology · 1996 · 1.2K citations · Full text

Life Sciences, Immunology, Pathology +17

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

William E. Thierfelder, Jan M. van Deursen, Koh Yamamoto et al. · Nature · 1996 · 1.2K citations

Life Sciences, Cell Biology, Immunology +16

Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution

Frank Heller, Peter Florian, Christian Bojarski et al. · Gastroenterology · 2005 · 1.1K citations · Full text

Life Sciences, Immunology, Pathology +17