Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Birgit Oppmann, Robin Lesley, Bianca Blom, +22

Immunity

InflammationCytokineBiological Activities SimilarImmune RegulationImmunology +6

Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

Robert M. Hoek, Sigrid R. Ruuls, Craig A. Murphy, +9

Science

ImmunologyRedox BiologyCellular PhysiologyOxidative StressNeuroinflammation +17

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells

Jenny Mjösberg, Jochem H. Bernink, Korneliusz Golebski, +7

Immunity

CytokineTranscriptional RegulationCell RegulationInnate Lymphoid CellsImmunology +9

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria

Jochem H. Bernink, Lisette Krabbendam, Kristine Germar, +11

Immunity

InflammationCytokineAutoimmune DiseaseMucosal ImmunologyInnate Immune System +11

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

Mirjam H.M. Heemskerk, Bianca Blom, Garry P. Nolan, +5

The Journal of Experimental Medicine

Human ThymusLymphocyte DevelopmentT-regulatory CellImmunologyNk Cells +14

DAP12-Deficient Mice Fail to Develop Autoimmunity Due to Impaired Antigen Priming

Alexander B. H. Bakker, Robert M. Hoek, Adelheid Cerwenka, +7

Immunity

Impaired AntigenAutoimmune DiseaseAutoantibody ProductionDap12-deficient Mice FailImmunology +8

Generation of Interferon α–Producing Predendritic Cell (Pre-Dc)2 from Human Cd34+ Hematopoietic Stem Cells

Bianca Blom, Stephen Ho, S. V. Antonenko, +1

The Journal of Experimental Medicine

Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

J. Marius Munneke, Andreas T. Björklund, Jenny Mjösberg, +8

Blood

Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- γc-/- mice: functional inactivation of p53 in developing T cells

Ramón Gimeno, Kees Weijer, Arie C. Voordouw, +6

Blood

The ETS Transcription Factor Spi-B Is Required for Human Plasmacytoid Dendritic Cell Development

Remko Schotte, Maho Nagasawa, Kees Weijer, +2

The Journal of Experimental Medicine