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A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells

Dane Z. Hazelbaker, Amanda Beccard, Gabriella Angelini, Patrizia Mazzucato, Angelica Messana, Daisy Lam, Kevin Eggan, Lindy E. Barrett

Scientific Reports · 2020 · 39 citations · 34 references

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References

34

Embryonic Stem Cell Lines Derived from Human Blastocysts

James A. Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science · 1998 · 15.8K citations

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Biological insights from 108 schizophrenia-associated genetic loci

Kai-How Farh, Brendan Bulik‐Sullivan · Nature · 2014 · 8K citations · Full text

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CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Luke A. Gilbert, Matthew H. Larson, Leonardo Morsut et al. · Cell · 2013 · 3.7K citations · Full text

, , +6

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Luke A. Gilbert, Max A. Horlbeck, Britt Adamson et al. · Cell · 2014 · 2.8K citations · Full text

, , +7

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

Knut Woltjen, Iacovos P. Michael, Paria Mohseni et al. · Nature · 2009 · 1.8K citations · Full text

, , +5