Concepedia

Transgene Construct Design

Transgene Construct Design is a methodological framework in genetic engineering that specifies the structural and functional organization of exogenous DNA sequences, including regulatory elements and coding regions, to enable stable integration, precise expression, and heritability of desired traits in transgenic organisms.

51

Publications

3.4K

Citations

289

Authors

96

Institutions

Publications per year

2017–2026

7

Parents

Publications

51

I-SceI meganuclease mediates highly efficient transgenesis in fish

Violette Thermes, Clemens Grabher, Filomena Ristoratore et al. · Mechanisms of Development · 2002 · 534 citations

, , +14

Transgenic poplars: expression of chimeric genes using four different constructs

Jean‐Charles Leplé, Ana Cristina Miranda Brasileiro, M.F. Michel et al. · Plant Cell Reports · 1992 · 328 citations

, , +16

Regulation of Smooth Muscle α-Actin Expression In Vivo Is Dependent on CArG Elements Within the 5′ and First Intron Promoter Regions

Christopher P. Mack, Gary K. Owens · Circulation Research · 1999 · 239 citations · Full text

, , +14

Utilization of MHC Class I Transgenic Mice for Development of Minigene DNA Vaccines Encoding Multiple HLA-Restricted CTL Epitopes

Glenn Ishioka, John Fikes, Gary Hermanson et al. · The Journal of Immunology · 1999 · 163 citations · Full text

, , +17

Sequences Downstream of the Translation Initiation Codon Are Important Determinants of Translation Efficiency in Chloroplasts

Hiroshi Kuroda, Pál Maliga · PLANT PHYSIOLOGY · 2001 · 148 citations · Full text

, , +17

1–5 of 51

Authors

289

  1. CL
    Ching‐Yi Lin

    Chung Shan Medical University, Taiwan

    2 publications · 83 citations

    2

    h-index

  2. KJ
    Kyle J. Lauersen

    Bielefeld University, Germany

    2 publications · 79 citations

    2

    h-index

  3. HK
    Hsin‐Mei Ku

    National Chung Hsing University, Taiwan

    2 publications · 83 citations

    2

    h-index

  4. CG
    Clemens Grabher

    Karlsruhe Institute of Technology, Germany

    2 publications · 626 citations

    2

    h-index

  5. JW
    Joachim Wittbrodt

    Heidelberg University, Germany

    2 publications · 177 citations

    2

    h-index

1–5 of 289

Institutions

96

  1. Laboratoire de Neurobiologie Cellulaire et Moléculaire

    Gif-sur-Yvette, France

    2 h-index

    5 publications

    2.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    5 publications

    2.2K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    5 publications

    315 citations

  4. National Chung Hsing University

    Taichung, Taiwan

    2 h-index

    8 publications

    361 citations

  5. Commonwealth Scientific and Industrial Research Organisation

    Canberra, Australia

    2 h-index

    25 publications

    1.4K citations

  6. Max Planck Institute of Molecular Cell Biology and Genetics

    Dresden, Germany

    2 h-index

    8 publications

    240 citations

  7. Tohoku University

    Sendai, Japan

    1 h-index

    2 publications

    38 citations

  8. University of Portsmouth

    Portsmouth, United Kingdom

    1 h-index

    2 publications

    120 citations

1–8 of 96

Venues

  1. PLoS ONE

    3 publications · 186 citations

    3

    h-index

  2. Transgenic Research

    3 publications · 118 citations

    3

    h-index

  3. PLANT PHYSIOLOGY

    2 publications · 270 citations

    2

    h-index

  4. Development

    2 publications · 175 citations

    2

    h-index

  5. Nature Biotechnology

    2 publications · 77 citations

    2

    h-index

1–5