Concepedia

Discovery of hPRDX5-based peptide inhibitors blocking PD-1/PD-L1 interaction through in silico proteolysis and rational design

Sen Zou, Juanjuan Liu, Zhengyang Sun, Xiao Feng, Zhongbo Wang, Yuanyuan Jin, Zhaoyong Yang

Cancer Chemotherapy and Pharmacology · 2019 · 17 citations · 17 references

DOI

Concepts

References

17

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

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Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

Yasumasa Ishida, Yasutoshi Agata, Kei‐ichi Shibahara et al. · The EMBO Journal · 1992 · 3.2K citations · Full text

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PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

, , +14

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Kaori Sakuishi, Lionel Apétoh, Jenna M. Sullivan et al. · The Journal of Experimental Medicine · 2010 · 2.1K citations · Full text

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Expression of Programmed Death 1 Ligands by Murine T Cells and APC

Tomohide Yamazaki, Hisaya Akiba, Hideyuki Iwai et al. · The Journal of Immunology · 2002 · 946 citations · Full text

, , +15