Concepedia

A Maitake (<i>Grifola frondosa</i>) polysaccharide ameliorates Alzheimer's disease-like pathology and cognitive impairments by enhancing microglial amyloid-β clearance

Yao Bai, Ling‐Ling Chen, Yao Chen, Xinmeng Chen, Yilong Dong, Shangyong Zheng, Lei Zhang, Weiyuan Li, Jing Du, Hongliang Li

RSC Advances · 2019 · 47 citations · 18 references

DOIFull text

Open access

Concepts

Abstract

immunomodulatory action, and dietary supplementation with PGM may provide potential benefits on brain aging related memory dysfunction.

References

18

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

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Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

Anthony J. Martorell, Abigail L. Paulson, Ho‐Jun Suk et al. · Cell · 2019 · 797 citations · Full text

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GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

Seonmi Jo, Oleg Yarishkin, Yu Jin Hwang et al. · Nature Medicine · 2014 · 773 citations · Full text

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Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

Carlo Condello, Peng Yuan, Aaron Schain et al. · Nature Communications · 2015 · 746 citations · Full text

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Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease

Hong Lian, Alexandra Litvinchuk, Angie C.A. Chiang et al. · Journal of Neuroscience · 2016 · 600 citations · Full text

, , +17