Peng Yuan

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang, Tyler K. Ulland, Jason D. Ulrich et al. · The Journal of Experimental Medicine · 2016 · 819 citations · Full text

Amyloid β, Immunology, Immune Regulation +21

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

Peng Yuan, Carlo Condello, C. Dirk Keene et al. · Neuron · 2016 · 760 citations · Full text

Alzheimer's Disease, Amyloid Compaction, Medicine +10

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

Robert Hill, Peng Yuan, Sasidhar Murikinati et al. · Neuron · 2015 · 722 citations · Full text

Ischemic Brain Is, Neurovascular Disease, Cerebral Vascular Regulation +18

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques

Carlo Condello, Peng Yuan, Aaron Schain et al. · Nature Communications · 2015 · 676 citations · Full text

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

Swetha Gowrishankar, Peng Yuan, Yumei Wu et al. · Proceedings of the National Academy of Sciences · 2015 · 384 citations · Full text