Concepedia

Prolonged half-life of small-sized therapeutic protein using serum albumin-specific protein binder

Tae Yoon Kim, Jinho Park, Ha Eun Shim, Dae Seong Choi, Dong‐Eun Lee, Ji‐Joon Song, Hak‐Sung Kim

Journal of Controlled Release · 2019 · 27 citations · 22 references

Concepts

Life SciencesPharmacokineticsPharmacologyBioavailabilityClinical BiochemistryDrug DeliveryProtein AggregationProtein BindingProtein CharacterizationProtein StructureProtein-ligand BindingAlbumin AdsorptionMetabolic Half-lifePlasma Protein Binding CapacityProtein Binding KineticsProtein Half-lifeProtein-bound Half-lifeSerum Protein Binding

References

22

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

Jesper Lau, Paw Bloch, Lauge Schäffer et al. · Journal of Medicinal Chemistry · 2015 · 1K citations · Full text

Pharmacy, Endocrinology, Pharmacology +17

Biopharmaceutical benchmarks 2010

Gary Walsh · Nature Biotechnology · 2010 · 759 citations

Potent Derivatives of Glucagon-like Peptide-1 with Pharmacokinetic Properties Suitable for Once Daily Administration

Lotte Bjerre Knudsen, Per F. Nielsen, Per Olaf Huusfeldt et al. · Journal of Medicinal Chemistry · 2000 · 687 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Albumin-based drug delivery: harnessing nature to cure disease

Maja Thim Larsen, Matthias Kuhlmann, Michael Lykke Hvam et al. · Molecular and Cellular Therapies · 2016 · 661 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

Recent advances in (therapeutic protein) drug development

H. A. Daniel Lagassé, Aikaterini Alexaki, Vijaya L. Simhadri et al. · F1000Research · 2017 · 497 citations · Full text

Engineering, Biotechnology, Pharmaceutical Biotechnology +12