Concepedia

Protein Binding Kinetics

Protein Binding Kinetics is a pharmacokinetic process that describes the rate and extent of reversible interaction between drugs and plasma proteins, distinguishing it from other distribution mechanisms by its dependence on binding affinity, protein concentration, and dissociation dynamics.

613

Publications

32.5K

Citations

2.4K

Authors

717

Institutions

Publications per year

2017–2026

100

Parents

Publications

613

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab

Nicholas Papadopoulos, Joel Martin, Qin Ruan et al. · Angiogenesis · 2012 · 1K citations · Full text

, , +15

Speeding molecular recognition by using the folding funnel: The fly-casting mechanism

Benjamin A. Shoemaker, John J. Portman, Peter G. Wolynes · Proceedings of the National Academy of Sciences · 2000 · 990 citations

, , +17

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

Peter J. F. Henderson · Biochemical Journal · 1972 · 524 citations · Full text

, , +15

Binding of Diffusible Molecules by Macromolecules: Rapid Measurement by Rate of Dialysis

Sidney P. Colowick, Frances C. Womack · Journal of Biological Chemistry · 1969 · 516 citations · Full text

, , +17

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

Jennifer A. A. Gubbels, Jennifer A. Belisle, Masanori Onda et al. · Molecular Cancer · 2006 · 443 citations · Full text

, , +14

1–5 of 613

Authors

2.4K

  1. SW
    Shaopeng Wang

    Arizona State University, United States

    11 publications · 751 citations

    11

    h-index

  2. NT
    Nongjian Tao

    Arizona State University, United States

    8 publications · 647 citations

    8

    h-index

  3. DS
    David S. Hage

    University of Nebraska–Lincoln, United States

    8 publications · 279 citations

    8

    h-index

  4. GM
    Guangzhong Ma

    Arizona State University, United States

    5 publications · 152 citations

    5

    h-index

  5. PJ
    Per Jemth

    Uppsala University, Sweden

    5 publications · 268 citations

    5

    h-index

1–5 of 2.4K

Venues

  1. Journal of Biological Chemistry

    JBC · 37 publications · 2.6K citations

    24

    h-index

  2. Biochemistry

    32 publications · 1.8K citations

    24

    h-index

  3. Analytical Chemistry

    22 publications · 1K citations

    17

    h-index

  4. PubMed

    Repository · 21 publications · 817 citations

    16

    h-index

  5. Journal of Pharmaceutical Sciences

    21 publications · 965 citations

    14

    h-index

1–5