Jesper Lau

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

Jesper Lau, Paw Bloch, Lauge Schäffer et al. · Journal of Medicinal Chemistry · 2015 · 959 citations · Full text

Albumin Affinity, Glycobiology, Peptide Science +19

Structure of the human glucagon class B G-protein-coupled receptor

Fai Siu, Min He, Chris de Graaf et al. · Nature · 2013 · 373 citations · Full text

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +6

Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain

S. Runge, Henning Thøgersen, Kjeld Madsen et al. · Journal of Biological Chemistry · 2008 · 290 citations · Full text

Crystal Structure, Molecular Modeling, Signal Transduction +13

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Gaojie Song, Dehua Yang, Yuxia Wang et al. · Nature · 2017 · 240 citations

Allosteric Modulators, Signal Transduction, Molecular Physiology +9

Small-molecule agonists for the glucagon-like peptide 1 receptor

Lotte Bjerre Knudsen, Dan Kiel, Min Teng et al. · Proceedings of the National Academy of Sciences · 2007 · 223 citations · Full text

Rat Pancreas, Glycobiology, Insulin Signaling +20