Psoriasis Targets and Therapy · 2019 · 32 citations · 52 references
Life SciencesNeurologyAutoimmunityImmunopathologyRheumatologyAutoimmune DiseasesMultiple SclerosisAutoinflammatory MechanismsMultiple Sclerosis AssociationsMultiple Sclerosis ImmunopathogenesisMultiple Sclerosis ImmunopathologyNarrative Literature ReviewPsoriasis ImmunopathologyPsoriatic Disease
The association of psoriasis (PsO) with other autoimmune and autoinflammatory diseases has long been a topic of interest. Although previous studies have attempted to clarify the specific relationship between PsO and multiple sclerosis (MS), it remains obscure, with limited and conflicting evidence regarding a link between the two entities. Herein, we review the etiology, pathogenesis, and treatment of each disease and present the available literature to-date regarding a possible relationship between PsO and MS. We conclude that further study is necessary to discern whether there may be a significant relationship between PsO and MS. In the meantime, clinicians may find it appropriate to screen for MS in patients with PsO, allowing for timely referral to a neurologist should it be necessary.
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Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis
Xavier Montalbán, Stephen L. Hauser, Ludwig Kappos et al. · New England Journal of Medicine · 2016 · 1.9K citations · Full text
Life Sciences, Immunology, Neurology +17