Concepedia

Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding

Sanjula P. Wickramasinghe, Justine Lempart, Hope E. Merens, Jacob Murphy, Philipp Huettemann, Ursula Jakob, Elizabeth Rhoades

Biophysical Journal · 2019 · 48 citations · 38 references

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38

A protein factor essential for microtubule assembly.

Murray Weingarten, Arthur H. Lockwood, S Y Hwo et al. · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Michel Goedert, Maria Grazia Spillantini, Ross Jakes et al. · Neuron · 1989 · 2.5K citations

, , +16

Neurodegenerative Tauopathies

Virginia M.‐Y. Lee, Michel Goedert, John Q. Trojanowski · Annual Review of Neuroscience · 2001 · 2.4K citations

, , +16

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

Michel Goedert, Ross Jakes, M. G. Spillantini et al. · Nature · 1996 · 1K citations

, , +15

Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( <sup>306</sup> VQIVYK <sup>311</sup> ) forming β structure

Martin von Bergen�, Peter Friedhoff, Jacek Biernat et al. · Proceedings of the National Academy of Sciences · 2000 · 1K citations · Full text

, , +17