Concepedia

Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy

Ana M. Moreno, Nathan Palmer, Fernando Alemán, Genghao Chen, Andrew Pla, Ning Jiang, Wei Leong Chew, Mansun Law, Prashant Mali

Nature Biomedical Engineering · 2019 · 126 citations · 75 references

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References

75

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

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Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations

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RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Giedrius Gasiūnas, Rodolphe Barrangou, Philippe Horvath et al. · Proceedings of the National Academy of Sciences · 2012 · 2.8K citations · Full text

, , +14

In vivo genome editing using Staphylococcus aureus Cas9

F. Ann Ran, Le Cong, Winston X. Yan et al. · Nature · 2015 · 2.7K citations · Full text

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