Concepedia

Vector Immunogenicity

Vector immunogenicity is the inherent capacity of a gene therapy vector to provoke an immune response in the host organism, distinguishing it from other vector properties by its specific role in activating innate and adaptive immune pathways against the delivered genetic construct.

195

Publications

13.4K

Citations

1.6K

Authors

428

Institutions

Publications per year

2017–2026

44

Parents

Publications

195

Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization

Yukio Sato, Mark Roman, Helen Tighe et al. · Science · 1996 · 1.1K citations

, , +17

Comparative Seroprevalence and Immunogenicity of Six Rare Serotype Recombinant Adenovirus Vaccine Vectors from Subgroups B and D

Peter Abbink, Angelique A. C. Lemckert, Bonnie A. Ewald et al. · Journal of Virology · 2007 · 516 citations · Full text

, , +16

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 <i>gag</i> Gene

Danilo R. Casimiro, Ling Chen, Tong‐Ming Fu et al. · Journal of Virology · 2003 · 398 citations · Full text

, , +17

A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

Matthew D. J. Dicks, Alexandra J. Spencer, Nick J. Edwards et al. · PLoS ONE · 2012 · 394 citations · Full text

, , +15

A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus

Gerd Sutter, Linda S. Wyatt, Patricia L. Foley et al. · Vaccine · 1994 · 291 citations

, , +16

1–5 of 195

Authors

1.6K

  1. DC
    David C. Montefiori

    Duke Medical Center, United States

    6 publications · 334 citations

    6

    h-index

  2. GD
    Georgia D. Tomaras

    Duke University, United States

    5 publications · 302 citations

    5

    h-index

  3. BM
    Bernard Moss

    National Institute of Allergy and Infectious Diseases, United States

    5 publications · 726 citations

    5

    h-index

  4. KA
    Katherine A. High

    Children's Hospital of Philadelphia, United States

    5 publications · 653 citations

    5

    h-index

  5. DH
    Dan H. Barouch

    Beth Israel Deaconess Medical Center, United States

    5 publications · 764 citations

    5

    h-index

1–5 of 1.6K

Institutions

428

  1. National Institutes of Health

    Bethesda, United States

    16 h-index

    64 publications

    4.6K citations

  2. University of Pennsylvania

    Philadelphia, United States

    15 h-index

    60 publications

    4K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    13 h-index

    57 publications

    4.8K citations

  4. Harvard University

    Cambridge, United States

    10 h-index

    59 publications

    9.4K citations

  5. Beth Israel Deaconess Medical Center

    Boston, United States

    8 h-index

    63 publications

    6.1K citations

  6. Thomas Jefferson University

    Philadelphia, United States

    7 h-index

    25 publications

    650 citations

  7. Fred Hutch Cancer Center

    Seattle, United States

    7 h-index

    29 publications

    1.7K citations

  8. Duke Medical Center

    Durham, United States

    7 h-index

    22 publications

    785 citations

1–8 of 428

Venues

  1. Journal of Virology

    JVI · 24 publications · 2.5K citations

    22

    h-index

  2. Molecular Therapy

    14 publications · 972 citations

    14

    h-index

  3. Vaccine

    15 publications · 789 citations

    14

    h-index

  4. PLoS ONE

    11 publications · 830 citations

    10

    h-index

  5. Gene Therapy

    10 publications · 928 citations

    10

    h-index

1–5