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A new class of acyclic 2-alkyl-1,2-diaryl (E)-olefins as selective cyclooxygenase-2 (COX-2) inhibitors

Md. Jashim Uddin, Praveen P. N. Rao, Md. Abdur Rahim, Robert McDonald, Edward E. Knaus

Bioorganic & Medicinal Chemistry Letters · 2004 · 21 citations · 14 references

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14

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

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Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

Meishiang Jang, Lining Cai, George Udeani et al. · Science · 1997 · 4.9K citations

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

Ravi G. Kurumbail, Anna M. Stevens, James K. Gierse et al. · Nature · 1996 · 1.9K citations

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Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen

S. H. Ferreira, Salvador Moncada, John R. Vane · Nature New Biology · 1971 · 934 citations

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

Peter Teismann, Kim Tieu, Dong‐Kug Choi et al. · Proceedings of the National Academy of Sciences · 2003 · 659 citations · Full text

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