Edward E. Knaus

Design and Synthesis of Celecoxib and Rofecoxib Analogues as Selective Cyclooxygenase-2 (COX-2) Inhibitors:  Replacement of Sulfonamide and Methylsulfonyl Pharmacophores by an Azido Bioisostere

Amgad G. Habeeb, Praveen P. N. Rao, Edward E. Knaus · Journal of Medicinal Chemistry · 2001 · 219 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis of Celecoxib Analogues Possessing a<i>N</i>-Difluoromethyl-1,2-dihydropyrid-2-one 5-Lipoxygenase Pharmacophore: Biological Evaluation as Dual Inhibitors of Cyclooxygenases and 5-Lipoxygenase with Anti-Inflammatory Activity

Morshed Alam Chowdhury, Khaled R.A. Abdellatif, Ying Dong et al. · Journal of Medicinal Chemistry · 2009 · 178 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Design and Synthesis of 4,5-Diphenyl-4-isoxazolines:  Novel Inhibitors of Cyclooxygenase-2 with Analgesic and Antiinflammatory Activity

Amgad G. Habeeb, Praveen P. N. Rao, Edward E. Knaus · Journal of Medicinal Chemistry · 2001 · 178 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Syntheses, Calcium Channel Agonist−Antagonist Modulation Activities, and Nitric Oxide Release Studies of Nitrooxyalkyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate Racemates, Enantiomers, and Diastereomers

Rudong Shan, Carlos Velázquez, Edward E. Knaus · Journal of Medicinal Chemistry · 2003 · 172 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Syntheses, Calcium Channel Agonist-Antagonist Modulation Activities, and Voltage-Clamp Studies of Isopropyl 1,4-Dihydro-2,6-dimethyl-3-nitro- 4-pyridinylpyridine-5-carboxylate Racemates and Enantiomers

Dean Vo, Wandikayi C. Matowe, Manian Ramesh et al. · Journal of Medicinal Chemistry · 1995 · 127 citations

Medicine, Biochemistry, Pharmacology +13