Stereoselective synthesis of 1-C-alkyl iminogalactitol derivatives, potential chaperones for galactosidase-linked LSDs: a real challenge

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Medicine, Clinical Sciences, Pharmacology +14

Enzymatic Defect in Fabry's Disease

Roscoe O. Brady, Andrew E. Gal, Roy M. Bradley et al. · New England Journal of Medicine · 1967 · 1.1K citations

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Exploring Cells with a Centrifuge

Christian de Duve · Science · 1975 · 281 citations

Engineering, Bioengineering, Cell Biology +5

Use of a recombinant bacterial fructose-1,6-diphosphate aldolase in aldol reactions: preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1,4-dideoxy-1,4-imino-D-arabinitol, and fagomine

Claus H. Von der Osten, Anthony J. Sinskey, Carlos F. Barbas et al. · Journal of the American Chemical Society · 1989 · 206 citations

Life Sciences, Biochemistry, Microbiology +6