David N. Garboczi

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

David N. Garboczi, Deborah T. Hung, Don C. Wiley · Proceedings of the National Academy of Sciences · 1992 · 694 citations · Full text

Human Class, Protein Assembly, Peptide Engineering +21

The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors

David Yin-wei Lin, Yoshimasa Tanaka, Masashi Iwasaki et al. · Proceedings of the National Academy of Sciences · 2008 · 445 citations · Full text

Crystal Structure, Immunology, Immunodominance +19

Two Human T Cell Receptors Bind in a Similar Diagonal Mode to the HLA-A2/Tax Peptide Complex Using Different TCR Amino Acids

Yuanhua Ding, Kathrine J. Smith, David N. Garboczi et al. · Immunity · 1998 · 437 citations · Full text

Signal Transduction, T-regulatory Cell, Hla Immunogenetics +9

The Molecular Defect Leading to Fabry Disease: Structure of Human α-Galactosidase

Scott C. Garman, David N. Garboczi · Journal of Molecular Biology · 2004 · 397 citations

Molecular Defect Leading, Fabry Disease, Mendelian Disorder +8

Four A6-TCR/Peptide/HLA-A2 Structures that Generate Very Different T Cell Signals Are Nearly Identical

Yuanhua Ding, Brian M. Baker, David N. Garboczi et al. · Immunity · 1999 · 364 citations · Full text

Signal Transduction, Adaptive Immune System, T-regulatory Cell +11