Concepedia

RHEB gene therapy maintains the chondrogenic characteristics and protects cartilage tissue from degenerative damage during experimental murine osteoarthritis

Sajjad Ashraf, Bongjun Kim, Sanghyuk Park, H. Park, S.-H. Lee

Osteoarthritis and Cartilage · 2019 · 14 citations · 26 references

DOI

Concepts

References

26

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

Florence Debacq‐Chainiaux, Jorge D. Erusalimsky, Judith Campisi et al. · Nature Protocols · 2009 · 1.6K citations · Full text

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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Ok Hee Jeon, Chaekyu Kim, Remi-Martin Laberge et al. · Nature Medicine · 2017 · 1.5K citations · Full text

, , +17

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

Siyoung Yang, Jonghwan Kim, Je‐Hwang Ryu et al. · Nature Medicine · 2010 · 521 citations

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Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2

Haiyan Zhang, C. X. Lin, Chun Zeng et al. · Annals of the Rheumatic Diseases · 2018 · 507 citations

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Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration

Hemanth Akkiraju, Anja Nohe · Journal of Developmental Biology · 2015 · 499 citations · Full text

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