Concepedia

Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors

Wen-Lin Tang, Yu Zhang, De-Xuan Hu, Hui Yang, Yu Qian, Jianwen Chen, Keli Agama, Yves Pommier, Lin‐Kun An

European Journal of Medicinal Chemistry · 2019 · 16 citations · 24 references

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References

24

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

, , +11

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

The mechanism of topoisomerase I poisoning by a camptothecin analog

Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

, , +14

A Model for the Mechanism of Human Topoisomerase I

Lance Stewart, Matthew R. Redinbo, Xiayang Qiu et al. · Science · 1998 · 703 citations

, , +14

Structures of Three Classes of Anticancer Agents Bound to the Human Topoisomerase I−DNA Covalent Complex

Bart L. Staker, M.D. Feese, Mark Cushman et al. · Journal of Medicinal Chemistry · 2005 · 535 citations · Full text

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