Systemic delivery of Eg5 shRNA-expressing plasmids using PEGylated DC-Chol/DOPE cationic liposome: Long-term silencing and anticancer effects in vivo

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +9

Expression profiling reveals off-target gene regulation by RNAi

Aimee L. Jackson, Steven R. Bartz, Janell M. Schelter et al. · Nature Biotechnology · 2003 · 2.4K citations

Life Sciences, Genetics, Molecular Biology +11

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

Life Sciences, Hematology, Molecular Genetics +9

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Emily Bernstein et al. · Genes & Development · 2002 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes

Joachim O. Rädler, Ilya Koltover, Tim Salditt et al. · Science · 1997 · 1.4K citations · Full text

Natural Sciences, Biochemistry, Biophysics +17